Why does your whole body ache when you have a cold?

Usually when a person has a cold, there are several reasons why the whole body aches and pains. Firstly, colds are all due to an infection caused by the body being invaded by, for example, bacteria, viruses, fungi and atypical pathogens, such as mycoplasma or chlamydia, when the immunity and resistance of the body is reduced. This is when endogenous pyrogens release inflammatory mediators such as bradykinin, leukotrienes, prostacyclin, and tumor necrosis factor. These factors then produce a sensitizing and pain-causing response in the body, which can cause pain throughout the body. Secondly, when you have a cold, your body is in the process of enhancing catabolism, which will consume excessive ATP in your body, consume heat and release excessive lactic acid in your body, which will accumulate in your body, especially in your skeletal muscles, which will also lead to pain in your body.