Steps for disengagement from the ventilator, preparation for disengagement from the ventilator, assessment of the patient’s clinical condition in accordance with the following factors: correction of the etiology leading to respiratory failure, control of infection, stabilization of vital signs, improvement in the function of all organs, the patient’s ability to breathe autonomously, and psychological readiness, at which point the patient can be disengaged. An autonomic breathing test should be performed for 120 minutes prior to deconditioning, usually with pressure support ventilation at a low pressure level, continuous positive airway pressure ventilation, or T-tube test ventilation for 120 minutes. If the criteria for a spontaneous breathing test are met, the patient is indicated to be able to tolerate the deconvolution and breathe spontaneously. If the patient is able to breathe on his own, and if the blood gas analysis is normal, and there is no significant change in wheezing symptoms, the endotracheal tube can be removed. Subsequent time should be monitored more intensively, because a small number of patients may have failure of withdrawal and extubation. Therefore, the decision to withdraw must be individualized according to the patient’s specific situation.