Glutathione 45 U/L is not serious because it is only slightly elevated, essentially at borderline values, which do not indicate liver damage and do not require treatment. Glutathione is the most abundant in the liver among all organs of the body, and other can also be present in the heart, kidneys and other organs. There are many enzymes in the liver, with the highest concentration of glutathione. Glutathione is found mainly in the liver cell membranes and is elevated whenever there is slight damage to the liver cells. Because the hepatocyte membrane is damaged, glutathione enters the bloodstream, resulting in an increase in serum glutathione in the peripheral blood. The elevation is so sensitive that 45 U/L is not a problem and does not require treatment.