Platelet 429 value is high, common causes: primary thrombocytosis and secondary thrombocytosis.
1. Primary thrombocythemia: it is a chronic myeloproliferative disease with insidious onset and slow progression, and the clinical manifestations vary in severity. Patients may not have any conscious clinical symptoms, and it is only discovered by chance when complicated by thrombosis, splenomegaly or elevated platelet count. The main clinical manifestations are recurrent thrombosis and bleeding.
2. Secondary thrombocytosis
(1) Infectious diseases: Thrombocytosis can be seen in viral, bacterial and mycoplasma infections, with respiratory tract infections being the most common. Bacteremia and toxemia can increase platelet destruction, leading to compensatory increase in platelets. Once the infection is controlled, both platelet lifespan and thrombocytosis can return to normal and do not require any treatment.
(2) Autoimmune diseases: bronchial asthma, anaphylactic purpura, etc. can lead to increased platelets. At present, it is believed that the patient has immune abnormalities, and after the endothelial damage, the subendothelial collagen and vascular hemophilia factor are exposed, and the platelets are activated and activated by adhesion, leading to an increase in the number of platelets.
(3) Anemia: anemia such as hemolytic anemia, nutritional anemia, and hemorrhagic anemia, with active myeloproliferative activity accompanied by increased platelets. Common symptoms include malaise, malaise, weakness, and dyspnea after exertion,
There may be other reasons for a high platelet 429 count, so it is recommended to seek medical attention to identify the cause.