The care of tumor patients should be carried out in a targeted manner according to the personality characteristics and psychological characteristics of patients in different periods. In addition to creating a quiet, comfortable and good recuperative treatment environment and improving patients’ motivation to fight with the disease, the following points should be done: (1) Keep abreast of patients’ psychological changes. To understand the patient’s true psychological state, we must be considerate and concerned about the patient’s occupation, culture, family, spouse and personal life situation, etc. We should also be familiar with the patient’s treatment plan and specific treatment methods. On the basis of the above information, we can conduct a comprehensive analysis and, according to their different occupations, psychological reactions and socio-cultural backgrounds, we can predict the psychological changes and psychological patterns that will or may occur in parallel or in advance, so that we can formulate effective preventive measures and psychological care programs, such as disease-specific care and person-specific care, in order to change “aftercare” into “beforehand control”. “(2) To enhance the patient’s ability to overcome the problem. (2) Enhance patients’ belief in overcoming the disease. Once some patients are informed that they have cancer, their desire to live will be reduced, while their desire to die will be increased. At this time, the main purpose of nursing care is to arouse the patient’s hope and belief in overcoming cancer. During the nursing process, the patient’s trust should be obtained with firm expressions and unquestionable words. Then use the fact that the patient’s condition has improved slightly to help the patient eliminate the bad psychological state. After the patient develops hope, the patient should be further encouraged to take up life matters within their ability and encourage them to dare to manage life. (3) Psychological care when the condition changes. When the patient has a variety of symptoms such as systemic failure, insomnia, pain, inability to eat, etc., the nursing staff should closely observe the changes in the condition and give the necessary supportive therapy. In addition to trying to improve the systemic condition, they should pay more attention to providing good psychological support to the patient, using examples of finally overcoming the disease through trials and tribulations to encourage and motivate the patient to fight against the disease. (4) Psychological care during the treatment process. Before the patient undergoes surgery, radiotherapy or chemotherapy, the patient should not only be informed of the necessity of such treatment, but also be informed of the possible adverse reactions during the treatment, so that the patient will have enough psychological preparation to actively overcome difficulties and actively cooperate with the treatment. (5) The role of language in psychological care of cancer patients. Just as Pavlov called the response of the organism induced by language as “universal conditioned reflex”, language is a tool to facilitate the mutual exchange of information and understanding between the companion and the patient, and it is also a prerequisite for successful nursing care. Patients often guess their condition based on the words and actions of their companions, so their words and actions not only represent the level of personal quality, but also directly affect the patient’s mood and confidence. Patients are exceptionally sensitive to verbal stimuli and have relatively low control over their personal behavior during psychological stages such as anger and sadness. For this reason, psychological care should first use language to warm their hearts, soothe their psychological wounds and regulate their mental balance.