Nails with vertical lines, if it is a nevus of the mother of nails, generally do not need special treatment; if it is a melanoma, it should be operated as early as possible; if it is a trauma, generally do not need special treatment; if it is a ringworm of the nails, it should be timely selection of antifungal treatment measures. 1. Nail nevus: it is a benign nevus under the nail, without other symptoms, generally does not need special treatment, more observation, regular review can be. 2. Melanoma: it is a malignant tumor originated from melanocytes, which needs to be operated as early as possible and treated with radiotherapy and chemotherapy. 3. Trauma: the bruise under the nail caused at night may also lead to vertical lines on the nail, generally no special treatment, most of them will be absorbed gradually, or grow out gradually with the metabolism of the nail. 4. Nail fungus: fungal infection of the nail bed and the subnail tissue caused by the disease, may also cause nails with vertical lines, nail thickening, brittle texture and other symptoms. You can use a knife or nail file to remove the diseased nail, and then apply cyclopirox ointment, amorolfine nail polish and other drugs. Nails with vertical lines, you need to go to the hospital for examination, to clarify the cause of the disease, and follow the doctor’s instructions for treatment, so as to avoid delaying the condition.