Crohn’s disease in children presents early with digestive symptoms as well as systemic symptoms. Initially, they most often manifest as fever and abdominal pain. Crohn’s disease is a chronic inflammatory disease that occurs in the digestive tract, and the cause of this disease is not yet known. Children with this disease first experience digestive symptoms. They usually manifest as bouts of diarrhea, abdominal pain, nausea and vomiting. Some children also experience pain and discomfort in the upper abdomen or around the umbilical cord, abdominal masses, and loss of appetite. Clinical symptoms are often atypical. In later stages, specific fistulas may appear, which may lead to other intestinal segments, mesentery, bladder, ureter and other parts of the body. It can also lead to generalized symptoms, such as malnutrition and intermittent fever. If the above symptoms of the baby should be timely medical care, complete colonoscopy, mucosal biopsy and other related tests to clarify the diagnosis and follow the doctor’s instructions for targeted treatment.