A low albumin globule ratio is a manifestation of cirrhosis. Patients with cirrhosis experience a decrease in albumin due to a decrease in the ability to synthesize albumin. The metabolism of globulin is also in the liver, and due to the decreased metabolic ability of the liver, globulin is instead elevated, and an inversion of the white-to-globulin ratio occurs. For patients with liver disease, it is recommended to clarify the cause of the liver disease, and if cirrhosis is caused by hepatitis B, lifelong treatment with oral antiviral drugs is required. The current first-line antiviral drugs include entecavir and tenofovir, which can effectively inhibit the replication of hepatitis B virus, reduce the incidence of hepatocellular carcinoma, and delay the progression of liver fibrosis and cirrhosis. In the case of cirrhosis caused by hepatitis C, oral antiviral drugs are also required for treatment.