Grade IV heart failure refers to the heart function of patients with heart failure is grade IV, at this time the patient’s life expectancy for how much can not be generalized, the patient’s life expectancy may be shortened, and even at any time there is sudden death. When the heart function of patients with heart failure is grade 4, it means that the patient’s cardiac function has been seriously damaged, and the patient can have symptoms such as wheezing even in the resting state, which may be accompanied by edema of both lower limbs, and at this time, the patient’s cardiac structure has also appeared to have pathologic changes, and the prognosis is not good. At present, the treatment of heart failure is mainly for the new quadruple therapy, which can be combined with sakubutra valsartan, dagliflozin, metoprolol and spironolactone, etc. If the patients insist on taking the medication for a long time, the condition control is stable and a better quality of life can be ensured, but the life expectancy will still be reduced compared with normal people; if the patients are not treated in a timely manner, there may be an acute heart attack at any time, and even sudden death may occur, and then life expectancy will be greatly shortened. If the patient is not treated in time, there may be an attack of acute heart failure at any time, and even sudden death may occur. Patients with heart failure need to ensure good living habits, quit smoking and drinking, and avoid physical labor while actively undergoing treatment, so as to obtain the best therapeutic effect.