If there is no effect after taking a course of Dapoxetine, you need to clarify the reason for the lack of effect under the guidance of your doctor before determining whether you need to continue taking it. Common reasons for the lack of effect include the dose, the way of taking, and the time of taking. 1. Dosage: Some people can’t get any effect when they take a low dose, but they can feel the effect when they increase the dose; at this time, they still need to continue to take it. 2. Dosage: It is recommended that the whole tablet be swallowed, not chewed, and that it be taken with a sufficient amount of lukewarm water. 3. Taking time: taking time is too short or too long, each person’s metabolism of the drug is different, usually taken within 1-3 hours. If you are not sure of the best time for you, you can try the drug at different times so as to find the right time for you. The use of dapoxetine hydrochloride can cause adverse reactions such as headache, dizziness, nausea and diarrhea. The drug is contraindicated in people with a known allergy to the product, in patients with a significant pathological condition of the heart, in patients with moderate and severe liver damage. The drug should also not be used in conjunction with thioridazine, strong cytochrome P450 3A4 inhibitors, and monoamine oxidase inhibitors. The drug is a prescription drug and should be used in strict compliance with the doctor’s instructions.