Diseases that cause severe obstructive pulmonary ventilation dysfunction include severe bronchial asthma as well as chronic obstructive pulmonary disease. Patients with chronic obstructive pulmonary dysfunction should be treated differently depending on the disease. If the patient is suffering from bronchial asthma, he/she should avoid allergens, inhale Symbicort or Sulindac, and inhale fast-acting bronchodilators such as Ventolin, Echolac, etc. if necessary. Oral leukotriene modulators and montelukast sodium are also required. Patients with low immune function can take oral transfer factor and pidomod to improve the immunity of the body. If the patient has severe main obstruction ventilation dysfunction due to chronic obstructive pulmonary disease, comprehensive treatment such as anti-infection, expectorant and asthma calming should be taken according to the condition.