Case: Qi of Xi’an is 48 years old, his father, brother and daughter all have different degrees of limb tremors, of which Qi’s symptoms are the most severe. According to Professor Wang Xuelian of the Department of Neurosurgery at Tangdu Hospital, the cause of four generations of grandchildren with hand tremors is a disease called “idiopathic tremor”, which generally has a family history, but the history progresses slowly and can be treated by means of drugs or brain pacemaker surgery. The company has been in the business for more than 30 years, and finally diagnosed the culprit hand trembling More than 30 years ago, Qi Mou felt his hands shaking slightly when he was nervous, angry, and crowded, he thought it was related to his introverted personality, so he did not treat it. After more than 10 years, the hand trembling situation has worsened, less flexible activities, a little disobedient, but less alcohol will reduce some of the symptoms; 5 years ago, he can hardly write, doing fine movements such as button shaking more powerful, along with the arms, head also shaking, violent shaking so that he eats and eats into difficulties. Qi said something like this: his father, who has passed away, and his brother, who is in his 50s this year, and his 22-year-old daughter also had hand tremors, but the symptoms were mild and not as severe as his own. After observing the symptoms and related tests, Professor Wang diagnosed Qi as suffering from “idiopathic tremor” and prescribed medication for him. Most patients with idiopathic tremor have a family history of idiopathic tremor is the most common movement disorder, mainly postural and motor tremor of the hands, head and other parts of the body, which is aggravated by concentration, nervousness, fatigue and hunger, and temporarily disappears in most cases after drinking alcohol. Because the main symptom is tremor, many patients with idiopathic tremor are initially misdiagnosed as Parkinson’s disease. In fact, these are two diseases, the difference being that Parkinson’s disease has other symptoms besides tremor, such as abnormal posture, motor retardation, mask face, and muscle rigidity, while tremor is the only symptom of idiopathic tremor. “The etiology and pathogenesis of idiopathic tremor is unclear. There are two peak periods of onset, one from 20 to 30 years old and the other from 40 to 60 years old, and most patients have a family history of the disease, which is an autosomal dominant genetic disorder. The human body has 23 pairs of chromosomes, 22 pairs of autosomes and one pair of sex chromosomes. Genes on the autosomes inherit the disease independent of gender, and offspring may inherit the disease if one of the father or mother has idiopathic tremor. The progression of idiopathic tremor is slow and can be left untreated if it has little impact on daily life; if it has a greater impact, it can be treated with medications such as insulin, but only half of the patients who take the drug have significant effects, and they can also consider switching to drugs such as paracetamol and clonidine. When all drugs are not effective, you can consider deep brain electrical stimulation (also called brain pacemaker, DBS) surgical treatment, the efficiency is more than 95%.