Scattered positivity for CD68 is generally considered a possibility for granulocytic sarcoma, cutaneous true histiocytic lymphoma, mastocytosis, and acute myeloid leukemia.
CD68 is a cytoplasmic glycoprotein that is a reliable marker for macrophages and is found in monocytes, granulocytes, large lymphocytes, mast cells, Langerhans’ giant cells, and melanoma, as well as macrophages, basophils, osteoblasts, synoviocytes, and dendritic reticulum cell sarcoma.
CD68 can be used to diagnose cutaneous true histiocytic lymphoma, granulocytic sarcoma, mastocytosis, and acute myeloid leukemia.
In addition, diseases such as acute myeloid leukemia and cutaneous true histiocytic lymphoma are hazardous and require active treatment, so patients are advised to consult a doctor in a timely manner to avoid delaying or aggravating their conditions.