Significant stenosis of the proximal lumen of the posterior descending branch may require cardiac stenting if there are symptoms of myocardial ischemia, stenosis of up to 70%, and unstable nature of plaques; on the contrary, it can be treated with oral medication as prescribed by the doctor, which should be analyzed in detail and should not be generalized. If the patient has symptoms of myocardial ischemia such as chest pain, chest tightness, dyspnea, shock, etc., or if the stenosis of the lumen reaches 70%, or if the nature of the plaque is unstable, then cardiac stenting may be required to reduce the risk of coronary artery occlusion, which may lead to myocardial infarction. If the patient does not have obvious symptoms of myocardial ischemia, the degree of lumen stenosis is less than 70%, the nature of the plaque at the stenosis is stable, the endothelium is smooth, and the risk of myocardial infarction is small, the patient can take medication as prescribed by the doctor, such as aspirin, Rosuvastatin, isosorbide mononitrate, candesartan, etc., and review the electrocardiogram on a regular basis, and consult the doctor in a timely manner in the event of any discomfort. Attention should also be paid to improve lifestyle, light diet, avoid fatigue and emotional excitement. If the lumen of the posterior descending branch is significantly narrowed, it is necessary to consult a doctor in time and follow the doctor’s instructions.