Generally speaking, you need to take estrogen for a long time after total uterine ovary removal, but you need to choose to take it according to your own situation. Ovaries are the main glands that secrete female hormones, after uterine ovary total excision, the estrogen level in the body will drop dramatically, leading to some adverse reactions in the body, such as insomnia and dreaminess, emotional outbursts, depression, decreased libido, etc. Supplementation of estrogen can alleviate these symptoms. However, patients must supplement estrogen under the guidance of a doctor to rule out contraindications to the use of estrogen, and blindly supplementing estrogen will increase the risk of breast cancer. Patients with total uterine ovary removal should take medication under doctor’s supervision and undergo regular review.