After oral anticoagulant drugs suddenly appeared prothrombin abnormality, it is recommended to improve the coagulation function, liver ultrasound, liver function and other tests under the guidance of the doctor to adjust the use of anticoagulant drugs as appropriate.
Prothrombin is mainly synthesized by the liver, especially needing vitamin K. Prothrombin abnormalities are common in the following situations: use of bicoumarin anticoagulants (such as warfarin, etc.), long-term use of antibiotics, serious liver diseases, vitamin K absorption disorders, and liver cancer.
Laboratory tests suggesting abnormalities in prothrombinogen should be treated accordingly, depending on the cause. If it is caused by liver disease, it is necessary to stop liver damage drugs and give liver-protecting treatment (glutathione). If anticoagulant medication is the cause, the medication should be reduced or discontinued depending on the patient’s condition, and vitamin K supplementation should be given.
The diagnosis and treatment of specific diseases need to be under the supervision of a physician.