The price of loratadine varies depending on what each manufacturer produces. The price varies greatly from manufacturer to manufacturer. The cheapest may range from five or six dollars a box, to more than ten or even forty or fifty dollars a box. Each one of them has a certain price difference due to its level of craftsmanship, or the reputation of the manufacturer, etc. In clinical use, the effects are usually similar, but some manufacturers may produce loratadine with a better process, may be slightly more expensive, and the antihistamine effect may be superior, so in clinical practice still need to be treated differently.