Ways to relieve severe insomnia include medication, acupuncture, and can also be improved through lifestyle. Lifestyle mainly includes proper exercise, appropriate participation in recreational activities, develop good work and rest habits, go to sleep and wake up on time, and do not stay up late. Drug treatment is generally applied sedative drugs, commonly used are eszopiclone, alprazolam, diazepam and lorazepam, but it is not recommended to apply for a long time, long time application of the brain has a certain inhibitory effect, and at the same time has a certain degree of dependence. If necessary, you can also take small doses of oral antipsychotic drugs, you can take oral quetiapine tablets, or oral mirtazapine, if necessary, acupuncture treatment. Patients may also experience severe insomnia when they have anxiety and depression, which is primarily treated with anxiolytic and antidepressant therapy. The main anti-anxiety drugs are tandospirone and buspirone, and the main antidepressant drugs are citalopram.