What is the etiology of erosive bone destruction?

Erosive bone destruction is defined as a malignant bone tumor with no definite boundary of destruction, no sclerotic ring envelope, and gradual migration between the tumor and normal bone. Erosive bone destruction is caused by malignant bone tumors and is also seen in bone infections. Malignant bone tumors, like other tumors, have complex pathogenesis factors, generally speaking, the endogenous conditions exist first, and the external causes occur through the endogenous ones. The endogenous factors include quality theory, genetic theory, endocrine theory, etc. The exogenous factors include chemical element substance and chronic stimulation by internal and external irradiation, viral infection theory, etc. Both osteochondroma multiforme and fibrous proliferative disease are related to family. Bone tumors mostly occur between the ages of 10-30, indicating that the exuberance of bone development and growth is related to the occurrence of tumors. Therefore, it can be assumed that during bone growth and maturation, the organism is more sensitive to the stimulation of the above factors, so that it can easily become tumor or tumor-like lesions. Benign tumors of bone can become malignant: for example, chondrosarcoma, osteochondroma, osteoblastoma, etc. can be malignant to sarcoma, and fibrous abnormal proliferation disease in tumor-like lesions can also be malignant to sarcoma. Some patients with bone tumor often recall the history of trauma to the affected part, such as sprain, bruise, etc. In fact, such trauma does not cause bone quality change, and osteosarcoma in fracture site is extremely rare; it is likely that when the tumor develops to a certain degree, the trauma prompts the symptoms to attract attention. Since this disease was first recorded in the Yellow Emperor’s Classic of Internal Medicine, Chinese doctors have further explored and supplemented the understanding and treatment of this disease from different aspects, which has gradually deepened the understanding of this disease. If the external evil attack, from the surface to the inside, reaches the bones and accumulates for a long time; if the blood channels are damaged due to fall and injury, the stagnant blood will not dissipate and become tumor; if the kidney is depleted due to insufficient endowment, or excessive exertion, or excessive room strain, the kidney energy will be depleted; if the kidney is the master of bone and marrow, the kidney energy will be depleted and the bones will become diseased; if the spleen and stomach are damaged due to indiscipline in eating, the spleen will not be healthy and healthy, the dampness and phlegm will be produced and will accumulate and become tumor; if the spirit is stimulated, the emotions are not smooth, and the five wills are too extreme, the yin and yang will be out of balance, the qi and blood will not be harmonized and the meridians will be blocked. The result is that the blood and qi are not in harmony and the meridians are blocked, resulting in bone tumors.