5-Hydroxytryptamine reuptake inhibitors, which are drugs for premature ejaculation. This type of drug mainly inhibits the reuptake of 5-hydroxytryptamine neurotransmitter in the central nervous system, thus increasing the content of 5-hydroxytryptamine neurotransmitter, which has a better effect on improving the ejaculatory control of the central nervous system. The main drugs used in this category are Bilirubin, Sertraline, Paroxetine and so on. The newest of these drugs is Bilirim, which has a fast metabolism in the body and is taken on demand before sex, and has no dependency.