The clinical significance of Th1 cytokines is that they can promote the survival and growth of Th1 cells, and the clinical significance of Th2 cytokines is that they can promote the proliferation of Th2 cells and play a role in humoral immunity.
Th1 cells are differentiated from Th0 cells induced by cytokines such as IL-12 and IFN-y, and are the typical cell type involved in cell-mediated inflammation and delayed-type hypersensitivity, and they are more important for immunization against intracellular pathogens.
The clinical significance of Th1 cytokines is that they promote the survival and growth of Th1 cells, maintain sufficient numbers of memory effector Th1 cells, and also serve to inhibit the formation of Th2 cells.
Th2 cells are a subpopulation of T cells capable of secreting Th2 type cytokines and belong to the CD4+ T cells.The clinical significance of Th2 cytokines is that they can promote the proliferation of Th2 cells and inhibit the proliferation of Th1 cells, and at the same time, assist in the activation of B cells, and play the role of humoral immunity.