Parkinson’s disease itself is not fatal though. However, as the disease progresses, a series of complications follow that inevitably affect the patient’s quality of life; they can lead to physical disability and even threaten the patient’s life. Motor complications are one of the main factors that cause disability in patients with Parkinson’s disease. The three main goals of Parkinson’s disease treatment The main causes of death in Parkinson’s disease patients with poorly controlled late symptoms include: decubitus ulcers, pulmonary infections, urinary tract infections, malnutrition, and venous thrombosis. For Parkinson’s disease treatment, it is internationally recognized to focus on three major treatment goals, namely, control of motor symptoms, improvement of non-motor symptoms, and prevention and treatment of motor complications. Parkinson’s disease progresses slowly, and most patients with Parkinson’s disease may develop motor complications after long-term treatment, and those with Parkinson’s disease with an age of onset less than 60 years are more likely to develop motor complications. Motor complications of Parkinson’s disease are divided into two main categories: “symptom fluctuations” (too little movement) and “hyperactivity” (too much movement). The typical symptom of “symptom fluctuation” is drug “end-of-dose phenomenon”, also known as reduced efficacy or end-of-dose deterioration, which is mainly manifested by the weakening of drug efficacy and shortening of drug duration of action; the other is “switch phenomenon The other is the “on/off” phenomenon, in which the patient can move around during the “on” period, but has significant motor impairment or retardation during the “off” period. Some patients suddenly stop while walking and their feet feel like they are stuck to the ground. At this point, the patient is very prone to fall, resulting in trauma or fracture. Another manifestation of motor complications is “anomia”, which commonly occurs in the limbs, facial muscles, head, neck, shoulders and back. These involuntary movements can be so large that if the patient is walking or walking up the stairs, he or she can easily fall down the stairs. In patients with advanced Parkinson’s disease, it is common for patients to fall and fracture their bones. Treatment In addition to adjusting medications to improve motor symptoms, deep brain electrical stimulation (DBS surgery) therapy has shown significant results. The procedure is performed by implanting electrodes at specific nuclei in the brain through stereotactic technology, and high-frequency electrical stimulation can suppress abnormal brain electrical activity, thus providing a cure. The treatment is precise, safe and reversible, and the goal of optimal symptom control will be achieved through postoperative programmed adjustment of parameters.