Portal vein widening means that the diameter of portal vein exceeds the normal range, generally it is common in abnormal pathological conditions, including congenital malformation of portal vein, portal vein trunk thrombosis, exogenous compression, autoimmune liver disease, viral hepatitis, it is necessary to clarify the specific problems and then make specific analysis. 1, congenital malformation of portal vein: the widening of portal vein is caused by abnormal development of portal vein, the symptoms are not obvious in early stage, but in late stage it may The early symptoms are not obvious, but the late symptoms may include weakness and portal hypertension, which can be observed by regular follow-up in the early stage, and surgical treatment is the main treatment after the middle stage; 2, portal vein trunk thrombosis: patients mostly have a history of vascular sclerosis, and the symptoms are similar to vascular variation, such as abdominal pain, ascites, splenomegaly, etc. The treatment is mainly anti-thrombotic, and the commonly used drugs include aspirin enteric tablets, clopidogrel, etc.; 3, exogenous compression: mainly the tissue around the portal vein The treatment is mainly to release the compression, such as lesion tissue removal; 4, viral hepatitis: the common ones are viral hepatitis B and viral hepatitis C, which are related to the related hepatitis virus infection. Early symptoms are atypical and late symptoms such as malaise, wasting, portal hypertension, portal vein widening, such as ascites, hypersplenism, and establishment of collateral circulation may appear. Treatment can be antiviral therapy, hepatoprotective drugs, such as taking recombinant DNA leukocyte interferon, lamivudine, famciclovir, diammonium glycyrrhizate, etc., and can also assist in reducing portal vein pressure, such as laparotomy for drainage, or surgery; 5. autoimmune liver disease: it is a hepatocellular lesion caused by autoimmune system diseases, with impaired liver function and cirrhotic signs The treatment can be liver-protective, such as taking polyene-phosphatidylcholine capsules and other drugs. In addition, ursodeoxycholic acid, adenosylmethionine and other bile-supporting drugs can be used, and liver transplantation can be performed for patients with liver failure; 6. Constrictive pericarditis: it can cause right heart failure, causing gastrointestinal tract and liver edema, resulting in increased portal vein pressure and widening of the portal vein, and is mainly treated for heart failure. For example, restricting sodium intake and using vasoactive drugs such as dobutamine and dobutamine for treatment.