Which movement disorders are amenable to brain stereotactic surgery?

Movement disorders, also known as extrapyramidal disorders, arise from dysfunction of the basal ganglia. The main manifestation is dysfunction of random motor regulation, and muscle strength, sensation and cerebellar function are not affected. They are categorized into two main types of manifestations: movement poverty and abnormal involuntary movements. Including Parkinson’s disease, chorea, hepatomegaly, torsion spasms, spasmodic cervical tilt and so on. Some movement disorders can be treated medically with good results. Some of them have little or no effect, but the side effects of the drugs are quite large and the patients suffer a lot. Cerebral stereotactic radiofrequency thermocoagulation is a major breakthrough in the treatment of movement disorders in recent years. The surgery is performed under local anesthesia, which is one of the least traumatic and safest neurosurgical procedures, and it can achieve unanticipated and satisfactory results for some of these diseases. For example, Parkinson’s disease, torsion spasm, spastic cervix, Tourette’s syndrome, delayed dyskinesia and so on. Brain stereotactic surgery includes temperature-controlled radiofrequency and brain pacemaker technology, of which temperature-controlled radiofrequency has been used in the treatment of Parkinson’s disease for more than 60 years, and is a very mature technology, especially in recent years, with the development of microelectrode technology, so that the efficacy and safety of the surgery has reached a new height. On the basis of brain stereotactic, microelectrodes are used to record and analyze the characteristics of cellular discharges to precisely locate the neuron cells that lead to movement disorders, and temperature-controlled radiofrequency is applied to them to weaken the cholinergic system, so that the neurotransmitters can reach a new equilibrium at a lower level to improve the symptoms, which is also known as the cytoknife. According to the observation and efficacy review of hundreds of surgeries performed by the Department of Functional Neurosurgery of Hunan Brain Hospital for more than 20 years, its effective rate is around 95%, and basically there is no serious complication. Brain pacemaker is a very small set of devices, including electrodes, wires and a small pulse generator. The technology is commonly known as “brain pacemaker” technology because it is similar to a heart pacemaker. These components are implanted in the body and do not affect the patient’s daily life. It uses stereotactic brain technology to implant stimulation electrodes into specific nuclei in the brain, and the high-frequency electrical stimulation emitted by the pulse generator implanted under the skin of the patient’s chest suppresses the abnormal electrical activity of neurons in the nuclei, thus achieving the goal of treating movement disorders. Its advantages are non-destructive, reversible and adjustable, safe and feasible surgery, simultaneous improvement of symptoms on both sides of the body, few postoperative side effects and few complications. It is the newest and most advanced surgical method for treating movement disorders. 1999 saw the introduction of brain pacemaker technology into China, but due to its high price, its popularity is far less than that of cytarabine surgery. Patients can choose the treatment that suits them according to their financial situation.