Gloushystericus (hysterical globus) is the subjective feeling of something unspecified or a mass that causes discomfort such as distension, pressure or obstruction at the level of the cricoid cartilage at the base of the pharynx. The abnormal motor function of this part is also known as cricopharyngeal dyskinesia, which is known as mei kuo qi in Chinese medicine. Half of the general population may experience this sensation intermittently, but it is more common in menopausal women. Patients have mostly psychogenic factors in the onset of the disease and have obsessive-compulsive concepts in their personality. Prevention and relief methods are as follows: patients with pharyngeal allodynia should not be overly panicked, go to the hospital for examination to rule out cancer, and usually keep a cheerful mood. Some studies have shown that psychological factors play a dominant role, providing strong evidence for the psychological treatment of patients with hysterical globus pallidus. In the treatment of dysthymic coccidioidomycosis, attention must be paid to the mental factors of the disease, and when the effect of simple biological treatment is poor or ineffective, it should be supplemented with psychological supportive treatment in time. For patients with suspected cancer, patient and careful explanation should be made and strong hints should be given to guide the patients to the correct understanding of the disease until the doubts are eliminated. Only by adopting an integrated treatment approach from the perspective of biological, psychological and social medical pathogenesis can better results be achieved.