Direct surgery is generally not recommended for middle and advanced stage of rectal cancer, and preoperative neoadjuvant radiotherapy can be carried out first, then surgery can be carried out. The specific conditions of each patient are different, so please consult your physician for specific treatment plan. Rectal cancer is a kind of malignant tumor occurring in the epithelial cells of rectal mucosa, and the treatment is mainly based on surgery, supplemented by radiotherapy and chemotherapy. The specific treatment method needs to be determined according to the stage of rectal cancer and the specific conditions of patients. Intermediate and advanced rectal cancer usually has metastasis in regional lymph nodes, and treatment not only requires radical resection, but also radiotherapy and chemotherapy. For middle and advanced rectal cancer, preoperative neoadjuvant radiotherapy can be carried out first to shrink the tumor and lower the stage, and then surgery can be carried out, which can improve the surgical resection rate and reduce the risk of local recurrence. If diagnosed with intermediate or advanced rectal cancer, please follow the doctor’s instructions for treatment.