After tooth extraction, if the pain is reduced by anti-inflammatory injections, you may not need to take painkillers; otherwise, you may take painkillers as prescribed by your doctor to relieve the symptoms. After tooth extraction, if the wound is too big or the operation time is long, anti-inflammatory treatment is needed, mainly including oral or intravenous anti-inflammatory drugs (anti-inflammatory injection), such as cefuroxime, metronidazole or ornidazole, etc., which can effectively prevent inflammation and pain caused by infection of the wound after the operation. However, if the above treatments are not effective in relieving pain, or if the body’s stress response to the wound causes pain, painkillers (e.g., ibuprofen) can be taken as prescribed by the doctor to relieve pain.