Most IgA nephritis patients’ kidney survival rate can be more than 10 years, that is, IgA nephritis patients need to go through more than 10 years since the onset of the disease to the stage of uremia, but for some patients with more severe symptoms and pathologic types, and poorer response to medication, it may be less than 10 years to develop into uremia. Certain patients with pathologic lesions such as crescent formation can present with acute renal failure at the onset of the disease, and with poor treatment, the patient’s renal function can progress to uremia in just a few years. So when the patient’s disease can progress to uremia, mainly according to IgA nephritis patient’s clinical manifestations, the degree of renal pathological lesions and the patient’s personal responsiveness to drugs and other factors related.