The main difference between Gentamicin Sulfate and Gentamicin is that Gentamicin Sulfate is a sulfate of Gentamicin, a multicomponent antibiotic, and both have different routes of administration. Gentamicin sulfate and gentamicin, the former is a derivative of the latter, but the two main pharmacological components are the same, are aminoglycoside antibiotics. Gentamicin sulfate can be administered orally if it is a tablet. If it is an injection, it needs to be injected intramuscularly or diluted and injected intravenously, whereas gentamicin is rarely absorbed orally and is mostly injected intramuscularly. Both are suitable for the treatment of sensitive gram-negative bacilli (such as Serratia marcescens, Escherichia coli, etc.), and both have ototoxicity, nephrotoxicity, etc., prone to hearing loss, renal injury and other adverse reactions, if necessary, should be used under the guidance of a professional pharmacist. Both are contraindicated in those allergic to gentamicin, and children should use this drug with caution.