Microsphere embolization for liver cancer interventional therapy is a kind of embolization material, which works to delay the disease. Microsphere embolization carries chemotherapeutic drugs and directly embolizes tumor blood vessels, while the chemical drugs can be slowly released to act on the tumor, thus achieving the effect of slowing down the deterioration of liver cancer. However, it should be noted that mere embolization of microspheres may lead to incomplete tumor necrosis and easily stimulate tumor blood vessel regeneration and metastasis of cancer cells, therefore, it should be combined with other therapies for joint treatment. The main treatment for liver cancer is surgery, and doctors will perform liver resection or liver transplantation according to the condition. At the same time, radiotherapy, chemotherapy, targeted drugs and immunotherapy drugs are used to carry out comprehensive treatment. Microsphere embolization is effective in treating liver cancer, but surgery and drugs are still needed to fight the cancer together. Liver cancer patients should actively follow the doctor’s prescription to avoid delaying their condition.