Ten years of paroxysmal pain in the right upper abdomen is considered to be suffering from cholecystitis, intrahepatic bile duct stones, hepatitis and other diseases, and different diseases have different treatments, which mainly include medication and surgical treatment. 1. Cholecystitis: the main symptom is pain in the upper abdomen, especially after meals or eating greasy food. To treat acute cholecystitis, antibiotic anti-infection treatment, such as amoxicillin, etc.; if septic cholecystitis occurs or the disease is further aggravated, surgical treatment should be considered. 2. Intrahepatic bile duct stones: the clinical manifestations of static intrahepatic bile duct stones are prolonged epigastric pain and discomfort; obstructive ones will manifest chest and abdominal pain and discomfort, fever, and symptoms of biliary obstruction. The treatment of intrahepatic bile duct stones is mainly surgical treatment, and it is safer to remove the stones as soon as possible. 3. Hepatitis: abdominal pain and distension, pressure pain in liver area, jaundice, spider nevus and other symptoms are easy to appear. If the symptoms are mild, you can protect the liver treatment, such as oral glycyrrhizic acid preparation; if liver failure occurs, timely surgical treatment is recommended. It is recommended that patients with ten years of paroxysmal pain in the right upper abdomen should consult the doctor in time, complete the relevant examinations, clarify the cause of the disease, and take active treatment to avoid delaying the condition.