If the following nine signs appear, be careful of the occurrence of Alzheimer’s disease. 1. Memory impairment. Often manifested as “losing everything”, “forgetting everything”, repeatedly asking the same question; 2, visual-spatial skills impairment. Can not accurately determine the location of objects, can not find their own room, bed, can not distinguish the right and left of clothes, anyway; 3, language barriers. Although he speaks like a man, but the listener can not hear his words, stuttering and ambiguous; 4, writing difficulties. The content of the writing does not make sense, even can not write their own names; 5, loss of use and loss of recognition. The original can skillfully ride a bike, swimming, after the disease will not, do not recognize their relatives and familiar friends face; 6, calculation difficulties. Shopping can’t be counted, and in serious cases, even the simplest addition and subtraction can’t be done; 7, poor judgment and distraction. 8, mental dysfunction. Often mania, hallucinations, personality changes, etc.; 9, motor disorders. Aimless walking back and forth, opening and closing doors everywhere, incontinence, etc.