Alzheimer’s disease in the early stages of these clinical manifestations; we start with the memory decline in the elderly, many older people will lament, lamenting that their memory is not as good as it used to be, generally speaking, the ability of the elderly to accept new knowledge is poorer than that of young people, reading books and newspapers is not necessarily remember as clearly as before, and occasionally will not be able to find things, but the degree of relatively mild, will not significantly affect the quality of life, such as cooking, Laundry. Doing housework is more or less the same as in the past, and the ability to socialize, the ability to deal with interpersonal relationships, and the ability to take care of oneself on a daily basis are not significantly affected, which belongs to the memory loss of normal elderly people. The early stage of Alzheimer’s disease is characterized by prominent memory impairment, with the patient forgetting things easily and often losing things. At the beginning, the patient forgets things that happened recently, such as the meal he ate a few hours ago. With the aggravation of dementia, the patient’s long-term memory is also affected, such as the inability to recall past experiences. In addition to memory impairment, some patients show emotional disorders, early emotional instability easily lose their temper, emotional vulnerability easily shed tears, easily depressed and sad when encountering small things, will be agitated because of small things, but also fear of fear, and so on. Some patients have cognitive disorders, which can be manifested as inattention, distracted thinking, repetitive speech, indecision and indecision, which are completely different from the previous performance of the smart and capable, as if they have changed a person. Some patients also have psychological disorders, due to their own memory loss, do not know where things can not be found, will suspect that someone else stole his things. Some patients also feel physically uncomfortable, thinking that they have a disease, and everywhere to seek medical examination, although failed to find out what abnormalities, and even the doctor explained that there is no physical disease, but the patient still feel pain. Some patients with low sexual function, but often suspected that the spouse has an affair outside, for this reason often in the family often quarrel, husband and wife discord. A few patients also have some abnormal behavior, become excessively thrifty, collect waste products everywhere, some patients think that the simple sketches drawn by themselves or others are works drawn by famous painters and collect them as treasures. Some patients will often go to the wrong house and can’t find the place when they arrive at a new environment. The specific symptoms of Alzheimer’s disease are categorized as follows: 1. Memory impairment: The initial symptom of Alzheimer’s disease is memory loss. Mainly manifested in the recent memory of forgetting, for example: a thing to him a few times will immediately forget, just placed things turn around and forget where to put it, cooking has been put on the salt after a while and put once again, just bought things forget to take away and they left, just be introduced to recognize friends, meet again because of forgetting the friends of the name and the embarrassing scene. On the other hand, the memory of past events with deep impressions, such as wars experienced in the past, participation in certain major events and political activities, and loss of loved ones, is better, which is what we call distant memory is still well maintained. However, with the development of the disease, the distant memory will also gradually decline, and even symptoms such as misrepresentation, fiction and delusion will appear. Such as the past as the present or just happened, several unrelated things together, Zhang Guanzhi, the last name of the things done by Zhang as baggage, and sometimes even to others from beginning to end of the story of a thing that has not happened at all. When the memory disorder is the most serious, patients do not recognize their own relatives, and even do not recognize themselves in the mirror or photos. 2. Gradual loss of orientation to time and place: patients can’t distinguish between time and place, not because they have problems with their consciousness, but because their cognitive ability, that is, their intelligence, has declined. For example, patients do not know what year, month and day it is, whether it is morning or afternoon, they do not know where they are, and they cannot find their way home after leaving home. 3.Calculation ability disorder: Decline in calculation ability is also an aspect of cognitive decline. In mild cases, the speed of calculation slows down significantly, and the person is unable to complete complex calculations or often makes obvious mistakes; in serious cases, the person is unable to perform simple addition and subtraction calculations, and even loses the ability to respond to numbers completely. 4.Decrease in comprehension and judgment: It is manifested in the inability to understand things around correctly, which directly affects the reasoning and judgment of things, and inability to distinguish between the main and secondary, essential or non-essential things, so that they can not deal with the problems correctly. 5.Language disorder 6.Thinking and emotion disorder: Thinking is often fragmentary, big things are ignored, but trivial things are entangled, accompanied by emotional retardation, indifference to others, and gradually develop into a completely blank and expressionless, or pediatric-like symptoms of euphoria are very prominent. In some cases, there are hallucinations, such as hallucinations, hallucinations, etc.; in some cases, there are fragmentary delusions, such as delusions of jealousy, stolen delusions, exaggerated delusions and so on. 7, personality and personality change: most people are selfish, subjective, or impatient, irritable, irrational, or anxious, suspicious. Some people are withdrawn, self-centered, uninterested in things around them, and lack of enthusiasm, which makes them look like two different people compared with those before the onset of the disease. 8, behavioral disorders: early manifestations of forgetfulness-based behavioral disorders, such as forgetfulness, loss of items, lost and wandering. In the middle stage, the behavioral abnormalities related to thinking and judgmental disorders and personality changes, such as day and night, wandering around, noisy; do not know whether it is warm or cold, disordered clothing, or even clothes as pants, hat as a sock; do not care about hygiene, do not distinguish between dirt and cleanliness, or even play with the toilet; do not know the dignity and inferiority of the male and female, and even have a tendency to hypersexuality. 9, action disorders: slow movement, unsteady walking, hemiplegia, or even bedridden, incontinence, unable to eat on their own, and eventually death.