If the patient has swelling and pain in the liver area, the following causes are mainly considered: 1. Consider chronic hepatitis, such as hepatitis B, hepatitis E, hepatitis A, etc., the patient’s liver function is abnormal. 2. Consider cirrhosis of the liver which is secondary to hepatitis, degeneration of liver cells or even necrosis. 3. Consider liver abscess. 4. Consider having liver tumor, usually malignant tumor as an occupying lesion, tumor growth is leads to swelling and pain in the liver area. If the patient has pain in the liver area, he should consult the gastroenterology department as soon as possible for relevant examinations, such as liver ultrasound and chest and abdomen CT, MRI, etc. If necessary, liver aspiration biopsy should be performed. To determine the specific cause of the disease so as to make targeted treatment, liver damage is irreversible. Therefore, patients should pay attention to avoid liver damage caused by drugs and food in daily life, and use liver-protective and antiviral drugs as early as possible if they have hepatitis and other diseases.