Polyuria is not necessarily a disease; healthy people can also experience temporary physiological polyuria when they drink too much water. In patients with polyuria, it is important to first determine whether it is an increase in urine volume or an increase in the number of urinations. Increased urine volume, also known as polyuria, refers to a 24-hour urine output of more than 2,500 mL. Persistent polyuria is pathological and is commonly associated with the following diseases: 1. endocrine and metabolic diseases, including uremia, diabetic hypokalemia and hypercalcemia. 2. polyuria caused by kidney disease. renal polyuria has a history of kidney disease, especially in patients with abnormal renal tubular performance, and can occur in patients with polyuria. Polyuria can occur in the polyuric phase of acute renal failure as well as in the polyuric phase of chronic renal failure. 3, solute polyuria can occur in patients who need to be treated with mannitol and sorbitol during treatment, and in patients who use diuretics.