After radiofrequency ablation surgery for liver cancer, usually there will be no pain for about 7 days, the exact duration of pain also needs to be based on the patient’s personal physical condition, the size of the tumor, the frequency and duration of ablation, and so on. Before radiofrequency ablation surgery for liver cancer, local anesthesia should be done and the radiofrequency probe is inserted into the tumor tissue, so no obvious pain will be felt. If the tumor of liver cancer is relatively large, under the effect of radiofrequency ablation treatment, a large amount of tumor tissue will be necrotic, and aseptic inflammatory reaction will occur locally, accompanied by inflammatory exudate, resulting in stimulation of liver peritoneum, and the pain in liver area will be more obvious, and usually there will be no pain in about 7 days after the operation. If some patients will have persistent pain in liver area after radiofrequency ablation surgery for hepatocellular carcinoma, they should consider the possibility of postoperative recurrence and infection, and it is recommended to go to the hospital for review as soon as possible, and do the liver intensive CT and magnetic resonance examination in time, so as to make clear the recovery of the liver after the surgery, and whether there is any recurrence or infection.