What drugs to take for high blood sugar need to be based on the individual’s specific situation, and should be taken under the guidance of a doctor, mainly including biguanide drugs, sulfonylureas, glycosidase inhibitors and other drugs. 1. Metformin drugs: commonly used metformin, by delaying and reducing the output of hepatic glycogen, to achieve the purpose of lowering blood glucose, but also has the effect of reducing body weight. It is suitable for patients with high blood sugar who are not satisfied with diet and exercise control and obese. 2. Sulfonylureas: such as glipizide, glimepiride, etc. These drugs can promote the secretion of insulin in the body, thus helping to reduce blood sugar. 3. Glucosidase inhibitors: such as voglibose, acarbose, etc., such drugs can reduce and delay the absorption of carbohydrates in the gastrointestinal tract, thus reducing postprandial blood sugar, mainly for patients with high postprandial blood sugar and no dietary control. Different hypoglycemic drugs have different indications, contraindications, efficacy, and may produce certain adverse reactions, it is recommended that patients use the drugs correctly under the guidance of a doctor, avoid self-medication, so as not to produce adverse effects on the body.