When men have testicular cancer or epididymitis, localized hidden pain and discomfort will appear. However, testicular cancer is a kind of malignant tumor with higher malignant degree, when palpation is made, the testicle will be hard locally, and at the same time, the testicle will increase in size, and the patient will not be accompanied by obvious local pain and fever. Testicular cancer also has distant metastasis, which can be diagnosed by biopsy of the tumor. Epididymitis is more commonly caused by infectious factors, and it is clear that it is a specific pathogenic bacteria, so it is an infectious disease. Generally, when epididymitis is present, patients will have high fever, local pain or secondary local septic infection, which will lead to the phenomenon of high fever, and anti-inflammatory symptomatic treatment is effective. Therefore, testicular cancer and epididymitis are two different types of diseases, and the treatment options are different, so testicular cancer and epididymitis can be clearly distinguished.