A very rough tongue like sandpaper may be caused by inflammation of the tongue papilla, white keratosis of the tongue, gastric ulcers and other reasons. 1. Inflammation of the papilla of the tongue: due to malnutrition, lack of vitamins and antibiotics, etc. can lead to redness and swelling of the papilla of the tongue, which can cause the tongue to have a granular sensation, very rough like sandpaper. 2. White keratosis of the tongue: due to external factors such as smoking, drinking, eating too hot, too spicy and other aspects of the stimulation, caused by local inflammation of the tongue mucosa, resulting in the surface of the tongue is very rough like sandpaper, or there are particles of hyperplasia of the symptoms. 3. Gastric ulcer: gastric ulcer may also cause tongue microecological abnormalities, so that the tongue flora disorders and the appearance of tongue thickening, thus causing the tongue is very rough like sandpaper feeling. If the symptoms of rough tongue like sandpaper are serious, the patient should go to the hospital in time to avoid delaying the treatment.