Inferior wall myocardial infarction is defined as an obstruction of the coronary artery innervating the inferior wall, resulting in ischemia and necrosis of myocardial cells distal to the obstructing vessel. Most inferior wall myocardial infarctions are due to obstruction of the right coronary artery, and the ECG shows pathological Q waves in leads II, III, and aVF with arch-back elevation of the ST segment. The right dominant coronary artery illustrates the posterior septum and posterior wall of the left ventricle, which is also supplied by the right coronary artery, while the left dominant coronary artery is supplied by the gyral branch of the left coronary artery. If the patient’s inferior wall is supplied by an anterior descending branch, it can be combined with an anterior interventricular myocardial infarction at the same time. If the patient is supplied by the right coronary artery, it can be combined with both posterior and right ventricular wall myocardial infarction. In conclusion, the different distribution of coronary arteries determines different sites of vascular obstruction on the myocardial surface and different sites of infarction.