Amoxicillin can be taken for colds in patients with dilated cardiomyopathy. Amoxicillin will not have an effect on cardiac metabolism, and drug contraindications are not present in dilated cardiomyopathy, so dilated cardiomyopathy patients with colds can take amoxicillin. It is suitable for infections caused by sensitive bacteria, such as respiratory tract infections such as pneumonia, trachea – bronchitis, tonsillitis, otitis media, etc.; genitourinary tract infections such as gonorrhea, urethritis, cystitis, pyelonephritis, etc.; skin soft tissue infections. Allergic to penicillin and penicillin skin test positive patients are prohibited; penicillin oral drugs must be asked for a detailed history of drug allergy and penicillin skin test before use. Patients with infectious mononucleosis application of amoxicillin prone to rash, should be avoided. When the course of treatment is long, patients should check the liver, kidney function and blood routine. Patients should consult a doctor when there is obvious discomfort.