Patient: description of disease (onset time, main symptoms, hospitalization, etc.): I was examined for hypertrophic cardiomyopathy in Jiangsu Provincial People’s Hospital 15 years ago. After that, I went to do some tests at intervals of 2 years. Have done ECG, dynamic ECG, arteriography, echocardiography and other tests. I have been taking Phentolac since then. The effect is not obvious. I would like to know if surgery is possible in my case. How much is the risk and how much is the cost? Yao Guihua, Department of Cardiovascular Medicine, Qilu Hospital, Shandong University, China: Generally, only when syncope occurs in hypertrophic obstructive cardiomyopathy, chemical ablation or surgical resection of hypertrophic myocardium in the left ventricular outflow tract should be considered in order to alleviate the obstruction; there is no surgical evidence for hypertrophic non-obstructive cardiomyopathy, and the long-term application of betalactam and other medications are used for the treatment of hypertrophic nonobstructive cardiomyopathy.