If the patient has mild symptoms after eating spoiled durian, or only slight dizziness and nausea, it is recommended to drink plenty of water and rest in bed. Drinking more water can increase gastrointestinal peristalsis and promote the body’s metabolism, which is conducive to the discharge of feces and toxins and can relieve the symptoms, and proper rest is conducive to recovery. If the patient has nausea, vomiting, diarrhea and other symptoms, you can take oral montelukast, simethicone, etc. to relieve the symptoms of diarrhea. If the patient is seriously ill with obvious abdominal pain, diarrhea, fever and other symptoms, it is recommended that he should go to the hospital for relevant examinations, such as routine blood and stool tests. If there is bacterial infection antibiotic treatment can be given, such as flavopiridol, haloperidol, etc. Special attention should be paid to the diet regulation, at this time, a light and easy to digest diet should be given priority, such as millet porridge, mung bean porridge, noodles, etc. Also, avoid eating spoiled durian.