Perianal folliculitis is caused by bacterial infection, it is recommended to ensure that the skin and mucous membrane around the anus are clean and avoid local moisture. It is recommended to wash the perianal skin as well as mucous membrane with warm water every night. If the lesions are not broken, you can use topical fusidic acid cream or mupirocin cream, ichthyol cream, etc., once in the morning and once in the evening. If it has been broken, it is recommended to apply wet compresses with raffinose solution or furacilin solution first, and then give topical application of cream when the lesions are dry. It is important to avoid eating spicy and irritating food, and avoid having feces around the anus, or other such as sweat and impregnation, which may lead to the aggravation of bacterial infection. For frequent flare-ups, it is necessary to check whether there is anemia or blood sugar abnormality, and control it promptly if there is any abnormality.