Herpes labialis is usually caused by herpes simplex virus infection, which is mainly manifested by the appearance of clusters of small blisters on the mouth and lips, accompanied by burning sensation, itching and discomfort. It can be healed through medication and daily life adjustments. At present, medication is the best way to heal herpes labialis relatively quickly, but a light diet is also needed to promote the healing of herpes labialis. There are two types of medications for herpes labialis, topical and oral, which should be used after a doctor’s visit. Topical medications include acyclovir cream and penciclovir cream, which can be applied on the herpes of the mouth and lips. Oral medications include acyclovir, valacyclovir or famciclovir, and if severe and acyclovir-resistant, phosphonates or cidofovir may be applied. If the herpes ruptures and then turns into an ulcer, neomycin cream or fusidic acid cream can be used to prevent infection. Along with medication, attention should also be paid to the need to avoid spicy and irritating foods in the diet to reduce irritation to the mouth and lips, so as not to aggravate the disease or affect recovery. In addition, it is important to get enough sleep, arrange work and rest time reasonably, combine work and rest, avoid staying up late, and do physical exercise appropriately to enhance physical fitness, which will help herpes labialis heal.