The pain on both sides of the buttocks during pregnancy can be caused by changes in hormone levels, nerve compression, calcium deficiency and other reasons. 1. Hormone level changes: during pregnancy, due to changes in hormone secretion levels, the pregnant woman’s body will also secrete relaxin, resulting in ligament laxity, which will appear in the manifestation of pregnancy buttock pain. 2. Nerve compression: During pregnancy, as the gestational weeks continue to increase, the uterus and fetus are also increasing in size, which may compress the sciatic nerve of pregnant women, resulting in pain on both sides of the buttocks during pregnancy can not turn over. This kind of pain is usually associated with certain positions, such as side-lying position when the pain may be relieved, standing position when the pain is aggravated. 3. Calcium deficiency: During pregnancy, a large amount of calcium in the pregnant woman’s body is provided to the growth and development of the fetus’s bones, which is prone to osteoporosis and may lead to pain on both sides of the buttocks. If the pain on both sides of the buttocks persists during pregnancy, cannot be relieved by changing the position and tends to worsen, it is recommended to consult a doctor in time, under the guidance of the doctor, complete the relevant examinations, identify the cause and treat the symptoms.