The treatment of slightly thickened synovial membrane of the knee joint should be based on different causes to choose the appropriate treatment, the common causes are synovitis, gout, rheumatoid arthritis, etc. The treatment includes general treatment, medication and so on. 1. Synovitis: pay attention to rest, avoid excessive activities and weight-bearing walking, such as pain, you can take oral non-steroidal such as celecoxib, meloxicam, etc., or nutritional cartilage drugs such as glucosamine. 2. Gout: pay attention to low purine diet, oral uric acid lowering drugs such as allopurinol and non-steroidal drugs such as ibuprofen. 3. Rheumatoid arthritis: pay attention to the warmth of the joint parts, eat a diet rich in high protein food, oral non-steroidal drugs such as diclofenac sodium, and anti-rheumatic drugs such as methotrexate. There may be other reasons for the thickening of the synovial membrane of the knee joint, so it is recommended that you go to the hospital in time for standardized treatment under the guidance of the doctor. The use of the above drugs should be in accordance with medical advice