Syphilis TPPA may indeed be clinically false positive, and the percentage is actually not very low, related to the fact that the patient may be infected with other diseases, and the limitations of the test. If you suspect that you have a false positive, you first need to rule out whether you are infected with other diseases, such as upper respiratory tract infection, pneumonia, active tuberculosis, wind heart disease, bacterial endocarditis, infectious hepatitis, liver cirrhosis, chronic nephritis, rheumatoid arthritis, and systemic lupus erythematosus, all of which may cause the occurrence of false positive syphilis. It is important to note that many pregnant women, as well as older adults, have been found clinically to develop false positive syphilis as well. If you are considering your own false positive syphilis, you can request to retest your syphilis antibody and other related tests after three months.