A drop of blood on the 40th day of pregnancy needs to be diagnosed in the hospital to find out the cause, if it is preterm labor, then it will be treated with fertility preservation, if it is ectopic pregnancy, scarred pregnancy, then terminate the pregnancy as soon as possible. Vaginal bleeding in early pregnancy is clinically common in cases of preterm miscarriage, ectopic pregnancy, scarred pregnancy, etc. Gynecological ultrasound examination (if the previous cesarean section, it is recommended to choose the vaginal ultrasound), blood HCG, progesterone examination can be improved. If there is no fetal heartbeat or buds on the 40th day after menopause, and if intrauterine pregnancy is confirmed, combined with the results of blood HCG and progesterone, preeclampsia is mostly considered, and can be treated with abortion preservation. For patients whose gestational sac is deposited in the scar of previous surgery, it is recommended to terminate the pregnancy as soon as possible, and there is a high risk of bleeding in the abortion, it is generally recommended to be hospitalized for abortion. For those who have not detected the gestational sac in the uterine cavity, ectopic pregnancy cannot be ruled out, and it should be combined with the changes in blood HCG to make a comprehensive judgment. Women once found pregnant, should closely observe the presence of abdominal pain, vaginal bleeding, once appeared should be timely hospitalization, identify the causes of symptomatic treatment, so as not to delay the time of treatment.