The difference between olmesartan ester tablets and amlodipine benzenesulfonate is mainly the difference in the type of antihypertensive drug, pharmacokinetics, adverse reactions, contraindications and so on:
1. Different types of antihypertensive drugs: amlodipine benzenesulfonate belongs to calcium antagonists, and olmesartan ester belongs to angiotensin receptor blockers.
2. Pharmacokinetics: Amlodipine benzenesulfonate is taken orally for 7~8 days and the blood concentration reaches steady state. Olmesartan ester reaches steady state in 3~5 days after oral administration.
3. Adverse reactions are different: amlodipine benzenesulfonate common adverse reactions are lower limb edema, facial flushing and headache, palpitations, dry mouth, increased sweating, weakness, change in bowel habits, muscle pain and so on. Olmesartan ester adverse reactions dizziness, bronchitis, diarrhea, hematuria, cough, chest pain, fatigue, joint pain, high potassium.
4. Contraindications: amlodipine benzenesulfonate contraindications hypotension, severe aortic valve insufficiency and so on. Contraindications of olmesartan ester include high blood potassium, bilateral renal artery stenosis, blood creatinine more than 265μmol/L, etc..
Therefore, the choice of specific antihypertensive drugs should be under the guidance of a doctor to choose a reasonable antihypertensive drug according to the condition.